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Dose–response curves for inhibition of water flow in erythrocytes by selected drugs. Erythrocytes were incubated for 15 min with compounds at the indicated concentrations prior to stopped-flow analysis. Each point is an average of three different preparations. The deduced EC50 values were 27 μM for NSC 670229, 49 μM for NSC168597, and 28 μM for NSC 301460.
