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. Author manuscript; available in PMC: 2011 Mar 8.
Published in final edited form as: Brain Res. 2010 Jan 15;1318:42–51. doi: 10.1016/j.brainres.2010.01.011

Figure 3. Induction of the ADP does not depend on voltage gated sodium channels but does require sodium ions.

Figure 3

A: A representative cell before (left trace) and after (middle left trace) application of muscarine resulting in an ADP. When 1 μM TTX is applied the ADP is blocked (middle right trace) until the depolarizing current is increased resulting in a smaller ADP (right trace). B: A representative cell before (left trace) and after (middle left trace) application of muscarine resulting in an ADP. When the cell is perfused with a nominally sodium free ACSF containing NMG substituted for NaCl the ADP is blocked (middle right trace) even after increased depolarization (right trace). C: Summary plot of the ADP area under different conditions. *p<0.05 compared to control. **p<0.05 compared to muscarine.