Figure 2. The interactions of IL-13Rα2 with IL-13.
The overall structure to the left is a ribbon depiction of IL-13 bound to a molecular surface of IL-13Rα2. Panel (A) View of the ‘site III’ interface showing the backbone β-sheet interactions between the c’ strand of IL-13Rα2 D1 and the CD loop strand of IL-13. Panel (B) View of the ‘site II’ interface, showing the interactions between the D2 and D3 loops of IL-13Rα2 and the A and D helices of IL-13. Interacting residues are shown as sticks, and polar interactions are drawn as dashed red lines.
