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. Author manuscript; available in PMC: 2011 Jan 1.
Published in final edited form as: Shock. 2010 Jan;33(1):56–63. doi: 10.1097/SHK.0b013e3181a7fb7c

Figure 5.

Figure 5

A. Effect of (-)-Deprenyl on BAK (BH3)-induced monolayer hyperpermeability. The FITC-albumin fluorescence intensity is significantly high in the BAK (BH3) peptide transfected group compared with the transfection reagent (TransIT) alone treated group *(p < 0.05; n = 5). Cells pretreated with (-)-deprenyl (10 μM) show a decrease in BAK (BH3)-induced hyperpermeability compared with the cells transfected with BAK (BH3) and not pre-treated with (-)-deprenyl. †(p < 0.05; n = 5). B. Effect of (-)-deprenyl on BAK (BH3)-induced ROS formation. In RLMEC, transfection of BAK (BH3) peptide shows increased red fluorescence indicating increased ROS formation compared with untreated control or (-)-deprenyl (10 μM) alone treated cells. (-)-Deprenyl (10 μM) pre-treated cells show less fluorescence.