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. 2010 Feb 4;151(4):1760–1772. doi: 10.1210/en.2009-0870

Figure 6.

Figure 6

PGE2, but not cGMP, causes cell retraction in tanycytes. A–D, Whereas a cell-permeable sGC product (Br-cGMP, 280 nm, 30 min) caused stress fiber formation in tanycytes (B), the addition of PGE2 (280 nm, 30 min), one of the most biologically active of COX products, caused acute tanycyte retraction (C). E, Bar graph illustrating the percentage of tanycytes that underwent retraction under the various treatments. ANOVA F(3,59) = 104.352, P < 0.001. Error bars, sem. *, P < 0.05, as compared with control.