Table 1.
Brain cytokines are up-regulated in mHFD compared with mCTR offspring
Gene | Fold increase |
---|---|
IL-1 family | |
IL-1β | 7.39a |
IL-1R1 | 1.76a |
IL-1F6 | 22.48b |
IL-1F7 | 2.35b |
BBB trafficking | |
CCL26 (eotaxin) | 4.02b |
CCR3 (eotaxin-R) | 7.53b |
CCL19 (MIP-3) | 3.01a |
CCL2 (MCP-1) | 3.09b |
The fold change for each gene was calculated as 2−ΔΔCt, where ΔΔCt = ΔCt (mHFD group) − ΔCt (mCTR group); n = 4–7. BBB, Blood-brain barrier.
P < 0.01.
P < 0.05.