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. 2010 Feb 22;151(4):1622–1632. doi: 10.1210/en.2009-1019

Table 1.

Brain cytokines are up-regulated in mHFD compared with mCTR offspring

Gene Fold increase
IL-1 family
 IL-1β 7.39a
 IL-1R1 1.76a
 IL-1F6 22.48b
 IL-1F7 2.35b
BBB trafficking
 CCL26 (eotaxin) 4.02b
 CCR3 (eotaxin-R) 7.53b
 CCL19 (MIP-3) 3.01a
 CCL2 (MCP-1) 3.09b

The fold change for each gene was calculated as 2−ΔΔCt, where ΔΔCt = ΔCt (mHFD group) − ΔCt (mCTR group); n = 4–7. BBB, Blood-brain barrier. 

a

P < 0.01. 

b

P < 0.05.