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. Author manuscript; available in PMC: 2011 Mar 1.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2009 Dec 17;30(3):518–525. doi: 10.1161/ATVBAHA.109.200733

Figure 3. Expression Clustering and Functionally Validated PPRE.

Figure 3

A. Expression clustering of genes up-regulated in at least one RZ-treatment group. All gene expression values have been log2 transformed and normalized to the appropriate control. Mice received rosiglitazone at either a low (3 mg/kg/day, L) or high (10 mg/kg/day, H) dose for either 2 (2d) or 14 (14d) days. Each column represents a sample, and each row a gene. Increasing intensity of red or green color indicates greater up- or down-regulation, respectively. Black indicates no change in expression. B. Association of PPARγ binding sites identified by Chip-ChIP in 3T3-L1 differentiated adipocytes with genes up-regulated in aorta in at least one RZ-treatment group. Only those genes expressed both in 3T3-L1 cells and aorta were included.