Figure 2. Autosomal sites identified as sex differentially methylated.

Human chromosomes 1-22 are arranged vertically. Methylation sites in each chromosome are plotted horizontally in blue line. Red dots present sites showing sex difference based 5% uncorrected false positive rate. The ones above blue lines are sites where females are more methylated than males. The ones below blue lines are sites where males are more methylated than females. a): result from saliva methylation data. 307 sites are methylated more in females than in males, while 273 sites are methylated more in males. b): results from blood cell verification data. 21 sites are methylated more in females than in males, while 15 sites are methylated more in males.