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. 2010 Apr 6;5(4):e10043. doi: 10.1371/journal.pone.0010043

Table 1. Overall univariate analysis of association of socio-demographic and treatment related factors with treatment default among new smear positive TB patients.

Factors Def N-389 Comp N-540 P value OR (95% C.I)
Patient related
<Median age (41 yrs) 195 268 0.88 1.020 (0.79–1.32)
Resident for <1year 21 31 0.82 0.94 (0.53–1.66)
Literate (Read & write) 208 339 0.004 0.68 (0.52–0.89)
Married 303 433 0.39 0.87 (0.63–1.19)
Employed 216 306 0.73 0.95 (0.73–1.24)
Patient sole earner 92 130 0.88 0.97 (0.72–1.33)
Had other commitments 96 64 0.00 2.44 (1.72–3.45)
Alcoholic 191 180 0.00 1.93 (1.48–2.52)
Smoker 205 232 0.003 1.48 (1.14–1.92)
Having nuclear Family 255 349 0.77 1.04 (0.79–1.37)
Treatment related
Poor knowledge of TB and treatment 156 125 0.000 2.22 (1.70–3.00)
Had associated illness 57 99 0.14 0.77(0.54–1.09)
Inadequate patient provider interaction 298 335 0.000 2.00 (1.48–2.71)
Address verification not done 257 320 0.03 1.34 (1.01–1.77)
DOT at Health center/sub Center 319 456 0.32 0.84 (0.59–1.19)
Distance to DOT center (< = 2km) 309 437 0.57 0.91(0.66–1.26)
Patient with instances of missed doses 207 425 0.000 3.25 (2.42–4.37)
DOT not done 170 197 0.03 1.35 (1.03–1.80)
Side effects to drugs 212 149 0.000 3.14 (2.39–4.14)
*Overlapping of working hours with DOT timing 52 78 0.71 0.93 (0.61–1.42)
*Out station duties during treatment 18 12 0.033 2.23 (1.05–4.72)
Family support 377 530 0.22 0.59 (0.23–1.49)
Poor support from health staff 34 6 0.000 8.52 (3.40–22.83)
Unsatisfied with services 72 10 0.000 12.04 (5.92–25.20)

*Only for employed patients.

Def – Defaulted, Comp-Completed, OR – Odds Ratio, CI – Confidence Interval.