Table 1. Overall univariate analysis of association of socio-demographic and treatment related factors with treatment default among new smear positive TB patients.
Factors | Def N-389 | Comp N-540 | P value | OR (95% C.I) |
Patient related | ||||
<Median age (41 yrs) | 195 | 268 | 0.88 | 1.020 (0.79–1.32) |
Resident for <1year | 21 | 31 | 0.82 | 0.94 (0.53–1.66) |
Literate (Read & write) | 208 | 339 | 0.004 | 0.68 (0.52–0.89) |
Married | 303 | 433 | 0.39 | 0.87 (0.63–1.19) |
Employed | 216 | 306 | 0.73 | 0.95 (0.73–1.24) |
Patient sole earner | 92 | 130 | 0.88 | 0.97 (0.72–1.33) |
Had other commitments | 96 | 64 | 0.00 | 2.44 (1.72–3.45) |
Alcoholic | 191 | 180 | 0.00 | 1.93 (1.48–2.52) |
Smoker | 205 | 232 | 0.003 | 1.48 (1.14–1.92) |
Having nuclear Family | 255 | 349 | 0.77 | 1.04 (0.79–1.37) |
Treatment related | ||||
Poor knowledge of TB and treatment | 156 | 125 | 0.000 | 2.22 (1.70–3.00) |
Had associated illness | 57 | 99 | 0.14 | 0.77(0.54–1.09) |
Inadequate patient provider interaction | 298 | 335 | 0.000 | 2.00 (1.48–2.71) |
Address verification not done | 257 | 320 | 0.03 | 1.34 (1.01–1.77) |
DOT at Health center/sub Center | 319 | 456 | 0.32 | 0.84 (0.59–1.19) |
Distance to DOT center (< = 2km) | 309 | 437 | 0.57 | 0.91(0.66–1.26) |
Patient with instances of missed doses | 207 | 425 | 0.000 | 3.25 (2.42–4.37) |
DOT not done | 170 | 197 | 0.03 | 1.35 (1.03–1.80) |
Side effects to drugs | 212 | 149 | 0.000 | 3.14 (2.39–4.14) |
*Overlapping of working hours with DOT timing | 52 | 78 | 0.71 | 0.93 (0.61–1.42) |
*Out station duties during treatment | 18 | 12 | 0.033 | 2.23 (1.05–4.72) |
Family support | 377 | 530 | 0.22 | 0.59 (0.23–1.49) |
Poor support from health staff | 34 | 6 | 0.000 | 8.52 (3.40–22.83) |
Unsatisfied with services | 72 | 10 | 0.000 | 12.04 (5.92–25.20) |
*Only for employed patients.
Def – Defaulted, Comp-Completed, OR – Odds Ratio, CI – Confidence Interval.