Table 6. Quebec household transmission study: Secondary pH1N1 attack rates among household members by 2008–09 TIV status.
Outcome Category and 2008–09 TIV Status | Children <18 y, N = 48 | RR (95% CI) Vaccinated Versus Unvaccinated Children | Adults ≥18 y, N = 72 | RR (95% CI) Vaccinated Versus Unvaccinated Adults | Total, N = 120 | RR (95% CI) Vaccinated Versus Unvaccinated Overall |
Respiratory symptoms | ||||||
Received TIV | 4/8 (50%) | 0.71 (0.35–1.47) | 13/24 (54%) | 0.96 (0.62–1.50) | 17/32 (53%) | 0.85 (0.59–1.22) |
Did not receive TIV | 28/40 (70%) | 1 | 27/48 (56%) | 1 | 55/88 (63%) | 1 |
Influenza-like illness (ILI) syndrome | ||||||
Received TIV | 3/8 (38%) | 1.00 (0.38–2.66) | 8/24 (33%) | 3.20 (1.17–8.74) | 11/32 (34%) | 1.51 (0.82–2.80) |
Did not receive TIV | 15/40 (38%) | 1 | 5/48 (10%) | 1 | 20/88 (23%) | 1 |
Any PCR-confirmed pH1N1 | ||||||
Received TIV | 2/8 (25%) | 0.59 (0.17–2.06) | 12/24 (50%) | 2.18 (1.13–4.20) | 14/32 (44%) | 1.38 (0.84–2.26) |
Did not receive TIV | 17/40 (43%) | 1 | 11/48 (23%) | 1 | 28/88 (32%) | 1 |
ILI is defined as fever + cough + one or more of sore throat, myalgia, arthralgia, headache, or prostration.