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. 2010 Apr 1;5(4):e10017. doi: 10.1371/journal.pone.0010017

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This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.

This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration, which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.

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Odds ratios of severe malaria associations with the rs5751876 C allele are represented for each study as a grey box with a horizontal line. The mid-point of the line represents the odds ratio and the extreme points of the line represent the 95% CI. The contribution of each study to the meta-analysis is represented by the area of the grey box. The solid vertical line presents an odds-ratio of 1 (no association). The diamond at the bottom presents the overall odds ratio and CI: OR = 1.12 (95% CI: 1.02–1.23), P = 0.024. Cochran's Q-test for heterogeneity on 4 degrees of freedom: P = 0.651.