Table 1. SNP allele frequencies in the Gambian and Malawian case-control and family trio studies.
Gene | Assay | 1 Alleles | Gambia CC | Gambia Trio | Malawi CC | Malawi Trio |
ADCY9 | rs2238432 | C/T | 0.28 | 0.28 | 0.30 | 0.28 |
rs2230739 | A/G | 0.16 | 0.16 | 0.09 | 0.08 | |
rs3730119 | C/T | 0.26 | 0.27 | 0.25 | 0.25 | |
rs10775349 | C/G | 0.20 | 0.21 | 0.20 | 0.21 | |
rs8047038 | C/T | 0.31 | 0.30 | 0.30 | 0.30 | |
ADORA2A | rs3761422 | C/T | 0.28 | 0.28 | 0.31 | 0.30 |
rs2267076 | C/T | 0.27 | 0.27 | 0.30 | 0.29 | |
rs9624472 | A/G | 0.23 | 0.23 | 0.16 | 0.16 | |
rs5751876 | T/C | 0.39 | 0.40 | 0.30 | 0.30 | |
ADORA2B | rs2535611 | T/C | 0.03 | 0.03 | 0.13 | 0.11 |
rs11654 | G/C | 0.32 | 0.30 | 0.22 | 0.23 | |
rs2286796 | G/A | 0.37 | 0.30 | 0.22 | 0.23 | |
rs2302416 | G/A | 0.29 | 0.30 | 0.31 | 0.33 | |
ADRBK1 | rs12285582 | T/C | 0.40 | 0.40 | 0.29 | 0.28 |
rs948988 | G/A | 0.39 | 0.40 | 0.28 | 0.27 | |
rs7934433 | C/T | 0.14 | 0.12 | 0.28 | 0.30 | |
GNB3 | rs3759348 | G/A | 0.26 | 0.26 | 0.29 | 0.32 |
rs5443 | T/C | 0.18 | 0.16 | 0.16 | 0.16 | |
rs5446 | C/T | 0.46 | 0.49 | 0.50 | 0.48 | |
RGS2 | rs7531013 | G/A | 0.44 | 0.42 | 0.24 | 0.26 |
rs2179652 | T/C | 0.44 | 0.38 | 0.25 | 0.25 | |
rs2746073 | T/A | 0.02 | 0.01 | 0.06 | 0.05 |
Major allele/minor allele. CC: Case-control.