Table 5.
Case number and types of adverse drug reactions caused by forms of medication drugs and their main clinical symptoms
| Types of adverse drug reactions | Oral intake | Injection | External use | Total | Main clinical symptoms |
|---|---|---|---|---|---|
| Anaphylactic shock | 19 | 108 | 1 | 128 | Sweating, palpitations, blood pressure dropping, heart rate increasing, loss of consciousness |
| Skin and other attachment | 360 | 580 | 322 | 1262 | Hemorrhagic erythematous eruption all over the body, urticaria pruritus, local skin rashes |
| Digestive system | 96 | 351 | 12 | 459 | Liver damage, anorexia, inappetence, bellyache, diarrhoea, vomiting, gastrointestinal tract damage, inflammatory gastrointestinal mucosa disease, oesophagitis, gastrointestinal ulcers and bleeding, disturbance of absorptive function, pancreatitis, etc. |
| Urinary system | 135 | 166 | 0 | 301 | As to the degeneration of renal tubule, the impairment of renal proximal convoluted tubules is obvious, showing necrotizing disease. The symptoms include lumbago, make water little or anuria, urinary incontinence, haematuria, proteinuria, cylindruria, azotemia, decrease in renal function, etc. |
| Respiratory system | 15 | 30 | 1 | 46 | Coughing, chest aches, obstruction of upper respiratory tract, choke, cyanosis, vocal cords oedema, bronchoscopy, dyspnoea, respiratory failure, etc. |
| Eye damage | 11 | 7 | 13 | 31 | Optic neuritis, blurred vision, conjunctival haemorrhage, eyelid oedema |
| Cardiovascular system | 48 | 83 | 0 | 131 | Chest distress, cyanosis, shortness of breath, chest panic, pale face, cold limbs, blood pressure decline or increase, muffled heart sounds, conduction block, ECG changes, etc. |
| Nervous system | 22 | 54 | 0 | 76 | Numbness of limbs, dizziness, headaches, somnolence, high fever, twitching, stupor, coma, confusion, respiratory failure, circulatory failure, incontinence, may cause death in extreme cases. |
| Fever | 56 | 17 | 1 | 74 | Chilling, fever, generalised malaise, upset. |
| Blood and endocrine system | 105 | 37 | 0 | 142 | Leucopenia, thrombocytopenia, gum bleeding, bone marrow depression, aplastic anaemia, DIC, milk secretion. |
| The others | 148 | 305 | 19 | 472 | Mental disorders, skin redness and necrosis, limb trembling, tinnitus, hallucination, facial palsies, hypokalaemia, hypoglycaemia |
| Total | 1015 | 1738 | 369 | 3122 |