Figure 3.
(a) Comparison of fluorescence signals between traditional amphiphilic PEG-coated QDs and proton-resistant QDs in simulated gastric fluids. Under similarly acidic conditions, QDs coated with traditional amphiphilic polymers (octylamine-modified polyacrylic acid) are both quenched and precipitated. (b) Absorbance and fluorescence spectra of proton-resistant QD at different etching times. Notice that there is no blue-shift to either absorbance or fluorescence and that > 50% of the fluorescence intensity remains at 60 min.