Table IV.

Pharmacokinetic Parameters for SMEDDS B and Capsule Suspension

Parameters	SMEDDS B	Capsule suspension
t max (h)	1 ± 0.44	1.36 ± 0.39
C max (ng/mL)	112.61 ± 9.13	69.24 ± 3.99
AUC0→t (ng h/mL)	607.93 ± 45.06	445.36 ± 70.50
(ng h/mL)	1,124.57 ± 79.66	893.72 ± 116.56
AUMC0→t (ng h/mL)	4,752.96 ± 102.70	3,848.13 ± 265.20
(ng h/mL)	37,933.75 ± 1,609.08	33,804.48 ± 1,761.19
(h)	33.73 ± 1.11	37.82 ± 1.40
Relative bioavailability (%)	178.70	–

SMEDDS self-microemulsifying drug delivery system, t _max time of peak concentration, C _max peak of maximum concentration, AUC _0→t area under the concentration time profile curve until last observation, area under the concentration time profile curve extrapolated to infinity, AUMC _0→t area under moment curve computed to the last observation, area under moment curve extrapolated to infinity, mean residence time