Table 3.
Relative risk (95% confidence interval) of myocardial infarction by current tobacco exposure in 11 472 women and 13 191 men. Results from Cox proportional hazards regression analysis
| Smoking status | Unadjusted*
|
Adjusted†
|
|||||
|---|---|---|---|---|---|---|---|
| Women | Men | Ratio | Women | Men | Ratio | ||
| Never smoker | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 | |
| Ex-smoker | 0.99 (0.71 to 1.38) | 1.14 (0.90 to 1.44) | 0.87 (0.58 to 1.30) | 1.05 (0.74 to 1.50) | 1.11 (0.86 to 1.42) | 0.95 (0.61 to 1.46) | |
| Current smoker: | |||||||
| Non-inhaling | 1.70 (1.31 to 2.21) | 1.26 (0.98 to 1.61) | 1.35 (0.94 to 1.94) | 1.82 (1.39 to 2.41) | 1.37 (1.06 to 1.78) | 1.33 (0.91 to 1.94) | |
| Inhaling: | |||||||
| 1-14 g/day | 2.59 (1.98 to 3.38) | 1.52 (1.19 to 1.95) | 1.70 (1.18 to 2.44) | 2.76 (2.08 to 3.68) | 1.60 (1.24 to 2.07) | 1.72 (1.18 to 2.53) | |
| 15-24 g/day | 2.99 (2.25 to 3.99) | 1.72 (1.37 to 2.17) | 1.74 (1.20 to 2.51) | 3.27 (2.42 to 4.42) | 1.75 (1.37 to 2.23) | 1.87 (1.27 to 2.75) | |
| >24 g/day | 3.31 (1.91 to 5.73) | 2.08 (1.60 to 2.69) | 1.60 (0.87 to 2.93) | 2.82 (1.45 to 5.46) | 2.09 (1.58 to 2.77) | 1.34 (0.66 to 2.75) | |
| Test for interaction‡ | P= 0.002 | P= 0.005 | |||||
*
Adjusted for age and cohort.
†
Cox regression model stratified by sex and adjusted for age, cohort of origin, smoking status, sex, systolic blood pressure, diastolic blood pressure, cholesterol, triglyceride, body mass index, education, alcohol, diabetes, physical activity, and height.
‡
Likelihood ratio test for interaction between smoking and sex.