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. Author manuscript; available in PMC: 2010 Jun 28.
Published in final edited form as: Chem Commun (Camb). 2009 Mar 10;(24):3497–3510. doi: 10.1039/b821865j

Fig. 2.

Fig. 2

Representative chemical structures and compositions for three different types of MRI contrast agents. Left panel, the chemical structure of a T1 agent, Omniscan™, and T1 relaxation mechanism; middle panel, TEM image of a T2 agent, 9 nm Fe3O4 nanoparticles, and T2 relaxation; right panel, the chemical structure of EuDOTAM3+, a PARACEST agent. A 2-pool exchange model for CEST mechanism and a representative Z-spectrum are illustrated.