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. Author manuscript; available in PMC: 2010 Jun 28.
Published in final edited form as: Chem Commun (Camb). 2009 Mar 10;(24):3497–3510. doi: 10.1039/b821865j

Fig. 7.

Fig. 7

(a) Schematic of a multifunctional polymeric micelle with cRGD surface functionalization and DOX and SPIO loading. (b, c) TEM images of cRGD-encoded and cRGD-free micelles showing the clusters of SPIO nanoparticles in the micelle core. The insets are corresponding cryo-TEM images. (d) Tumor growth inhibition for different micelle groups in A549 human lung tumor-bearing mice. (e) Off-resonance saturation MR images of A549 tumors treated with cRGD-encoded and cRGD-free micelles respectively. Modified from refs. 19 and 110. (Permission pending)