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. 2010 Feb 2;19(9):1805–1815. doi: 10.1093/hmg/ddq039

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Published by Oxford University Press 2010

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.5), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 2. — Receiver operating characteristic C statistics of haplotype E-1, SNPs rs2413396 and rs5750250, and combined genotypes of rs5750250 and rs11912763 as predictors of HIVAN, FSGS and H-ESKD. Statistics were calculated by counting the frequency with which, in random draws of cases and controls, the case has a more susceptible genotype than the control. For the E-1 and the SNPs, susceptibility of the genotype was taken to be the number of copies of the risk allele. For combined rs5750250 and rs11912763, susceptibility of the genotype was taken from the following ordering, from least to most susceptible, for rs5750250/rs11912763 genotypes: AA/GG or AA/AG; AG/GG or AG/AG; GG/GG; GG/AG; AG/AA or GG/AA.