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. Author manuscript; available in PMC: 2010 Apr 7.
Published in final edited form as: Biochemistry. 2009 Jun 9;48(22):5007–5017. doi: 10.1021/bi900196c

Figure 4.

Figure 4

Salt-dependent stability of acetylated and nonacetylated H2A- and H2A.Z-containing NCPs. (A) Profile of analytical ultracentrifuge analysis of nucleosomes containing H2A with a non-acetylated histone complement or acetylated H2A with an acetylated histone complement at 0 and 600 mM NaCl. D: free 155 bp DNA. N: nucleosome core particle. (B) Nucleosome stability analysis of H2A or H2A.Z with non-acetylated histone complement, acetylated H2A, or acetylated H2A.Z with acetylated complement. Results show the percentage of undissociated nucleosome core particles containing a full histone octamer [calculated from the ratio (%) of area under N in panel A at a given salt level to the area under N in the absence of salt].