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. Author manuscript; available in PMC: 2010 Apr 7.
Published in final edited form as: Twin Res Hum Genet. 2010 Feb;13(1):57–65. doi: 10.1375/twin.13.1.57

Table 2.

Multinomial Regressions Showing Associations of Trauma Classes, Parental Alcohol Problems and Familial Effects with Single and Co-Occurring Lifetime MDD and Panic Attack at 0, 1, 5, 10, 15, and 20 Years After First Traumatic Event

MDD or panic attack only MDD + panic attack

Years since first trauma N1 RR (95% CI) RR (95% CI)
0 4325
Assault class 2 6.0 (4.3 – 8.4)** 14.3 (8.4 – 24.5)**
Witness class 2.8 (2.2 – 3.5)** 3.9 (2.3 – 6.7)**
Parental alcohol problems 1.6 (1.3 – 2.0)** 2.3 (1.5 – 3.5)**
Familial effect 3 2.6 (1.6 – 4.2)** 2.5 (1.0 – 6.0)*
1 4287
Assault class 6.4 (4.5 – 9.0)** 14.7 (8.5 – 25.4)**
Witness class 2.8 (2.2 – 3.5)** 3.7 (2.2 – 6.5)**
Parental alcohol problems 1.7 (1.4 – 2.0)** 2.4 (1.6 – 3.6)**
Familial effect 2.8 (1.7 – 4.5)** 2.3 (0.9 – 5.8)
5 4130
Assault class 7.0 (4.8 – 10.0)** 14.2 (7.7 – 26.3)**
Witness class 3.0 (2.3 – 4.0)** 3.2 (1.6 – 6.5)**
Parental alcohol problems 1.6 (1.3 – 2.0)** 2.4 (1.5 – 4.0)**
Familial effect 2.9 (1.7 – 4.9)** 2.1 (0.7 – 5.9)
10 3930
Assault class 7.4 (4.9 – 11.1)** 9.8 (4.3 – 22.4)**
Witness class 3.1 (2.3 – 4.3)** 2.3 (0.8 – 6.9)
Parental alcohol problems 1.5 (1.2 – 2.0)** 2.8 (1.4 – 5.7)**
Familial effect 3.0 (1.7 – 5.4)** 2.4 (0.5 – 10.7)
15 3734
Assault class 7.6 (4.4 – 13.1)** 3.5 (1.0 – 12.3)*
Witness class 3.3 (2.1 – 5.2)** 1.7 (0.4 – 6.8)
Parental alcohol problems 1.6 (1.1 – 2.3)* 4.0 (1.5 – 10.5)**
Familial effect 3.3 (1.5 – 7.2)** 0.9 (0.1 – 6.4)
20 a 3625
Assault class 11.8 (5.7 – 24.4)**
Witness class 3.4 (1.7 – 6.8)**
Parental alcohol problems 1.7 (0.9 – 2.9)
Familial effect 1.9 (0.6 – 6.0)
1

Ns decrease as individuals with a first onset of MDD or panic attack before the beginning of the next time interval are removed from the risk set;

2

Control class is the reference category

3

familial effect modeled as interaction of twin zygosity (monozygotic = 1, dizygotic = 0) with co-twin status on MDD or panic attack (‘1’ if either)

a

MDD-only, panic attack-only, and MDD + panic attack categories were combined due to too few individuals left in risk sets for panic attack or MDD-only and MDD + panic attack to permit separate estimation. All regressions adjusted for respondent zygosity, gender, alcohol dependence, antisocial personality symptoms, and co-twin status on MDD and panic attack

*

p < .05

**

p < .01