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. Author manuscript; available in PMC: 2010 Apr 7.
Published in final edited form as: Methods Mol Biol. 2009;500:335–359. doi: 10.1007/978-1-59745-525-1_12

Fig. 3.

Fig. 3

Flow of information through regression analysis components. Communications between the components are controlled by gfit according to Model Description. During simulation of each experiment, independent variables from the experiment conditions and parameters are tested against constraints and combined into model input data. The input received by the model is guaranteed to be valid and to contain sufficient information for the simulation. Combining conditions with parameters keeps the model agnostic about the purpose of the simulation. Size of variables in model output depends on the input. The dependence is defined in Model Description and used by gfit to provide the input that will result in model output directly comparable with the measured variables for that experiment.