Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Dual Substrate Assay: Compound IC50 Values (uM)
| Compound | phospho-MK2 | phospho-ATF2 | substrate selectivity |
|---|---|---|---|
| SD-0006 | 0.20 ± 1.1 | 0.02 ± 1.1 | 0.09 |
| BIRB 796 | 3.6 ± 1.4 | 0.12 ± 1.1 | 0.03 |
| CMPD1 | 41 ± 2.2 | 27 ± 16 | 0.66 |
| Virtual Cmpd | 0.0019 ± 1.1 | 0.0006 ± 1.2 | 0.33 |
IC50's are shown ± standard error. Substrate Selectivity = (ATF2 IC50)/(MK2 IC50)
