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. Author manuscript; available in PMC: 2011 Apr 15.
Published in final edited form as: Arch Biochem Biophys. 2010 Feb 12;496(2):101–108. doi: 10.1016/j.abb.2010.02.004

Figure 4.

Figure 4

(a) Stereoview of a simulated annealing gradient omit map contoured at 2.8σ, in which L-lysine bound in the active site of human arginase I (monomer A) was omitted from the structure factor calculation. Manganese coordination and hydrogen bond interactions are indicated by red and green dashed lines, respectively; atoms are color coded as in Figure 2. (b) Superposition of the human arginase I-L-lysine complex (color coded as in (a)) and the B. caldovelox arginase-L-lysine complex (blue) [36].