Table 2.
Overall Quality of Life Comparison with Controls
| QOL measure | BMT | Control | p-value* |
|---|---|---|---|
| Number of patients | 214 | 186 | |
| Physical | Mean Score | Mean Score | |
| Physical Component (PCS) | 51.1 | 55.1 | <0.001 |
| Physical Function | 89.1 | 94.5 | <0.001 |
| Role Physical | 84.5 | 91.0 | 0.02 |
| Bodily Pain | 79.2 | 82.9 | 0.05 |
| General Health | 70.1 | 81.4 | <0.001 |
| Psychological | |||
| Mental Component (MCS) | 50.4 | 48.5 | NS |
| Depression | 0.57 | 0.53 | NS |
| Anxiety | 0.30 | 0.30 | NS |
| Cognitive | |||
| MMQ | 0.55 | 0.53 | NS |
| NBRS | 1.64 | 1.28 | 0.01 |
| QOL domains | N | N | |
| PCS <40 | 25 (12%) | 6 (3%) | 0.001 |
| MCS <40 | 34 (16%) | 36 (18%) | NS |
| Cognitive <−1 | 46 (21%) | 27 (14%) | 0.04 |
| Number of QOL problems | |||
| 0 | 149 (70%) | 146 (74%) | 0.04 |
| 1 | 29 (14%) | 33 (17%) | |
| 2 | 29 (14%) | 18 (9%) | |
| 3 | 6 (3%) | 0 |
Abbreviations: QOL = quality of life, BMT = bone marrow transplant patient group, PCS = physical component score of SF 36 <40 = abnormal functioning, MCS = mental component score of SF 36 <40 = abnormal symptoms. MMQ = modified memory questionnaire, NBRS = neurobehavioral rating scale.
*
Student’s t test. On the NBRS and MMD higher scores indicate more symptoms. On the RS cognitive, higher scores indicate fewer symptoms.