Table 3.
Multivariate Analysis of Risk Factors for Physical Function
| Variable | No. of Pts | SF-PCS* | SEE | p-value |
|---|---|---|---|---|
| Diagnosis | ||||
| Myeloid | 68 | −2.0 | (2.64) | 0.02 |
| Lymphoid | 69 | 3.9 | (3.24) | |
| CML | 24 | 1.0 | (3.19) | |
| NM | 53 | --- | ||
| Donor type | ||||
| Matched | 171 | -- | ||
| Mismatched | 31 | −3.2 | (1.79) | NS |
| Autologous | 12 | −7.4 | (2.75) | 0.008 |
| Gender | ||||
| Female | 170 | |||
| Male | 44 | 0.90 | (1.25) | NS |
| Prior Therapy | ||||
| Less | 143 | |||
| More | 71 | −3.5 | (2.24) | NS |
| Time post BMT | ||||
| <18 years | 129 | |||
| >18 years | 85 | −2.0 | (1.42) | NS |
Abbreviations: SF-PCS = Short Form 36 physical scale where higher scores indicate better functioning, Myeloid = acute myelogenous leukemia, myelodysplastic syndrome, juvenile myelomonocytic leukemia, Lymphoid = Acute lymphoblastic leukemia, Hodgkin Disease, Non-Hodgkin Lymphoma, CML = chronic myelogenous leukemia, NM = non-malignant includes aplastic anemia, immune deficiency, red cell aplasia. Matched = HLA identical siblings or unrelated donors, mismatched = HLA non-identical family members or unrelated donors. Prior therapy less = first remission therapy or no therapy, prior therapy more = second or subsequent remission or relapse therapy or cranial irradiation. SEE = Standard Error of the Estimate
Numbers reflect mean differences relative to reference group.
--- = reference group.