Table 4.

Multivariate Analysis of Risk Factors for Psychological Function

Variable	No. of Pts	CMS*	SEE	p-value	Depression*	SEE	p-value	Anxiety*	SEE	p-value	Satis*	SEE	p-value
Diagnosis
Myeloid	68	−2.30	(2.72)	NS	0.25	(0.17)	NS	0.21	(0.14)	NS	−0.09	(0.48)	NS
Lymphoid	69	1.68	(3.33)		−0.03	(0.21)		0.10	(0.17)		0.87	(0.59)
CML	24	0.47	(3.28)		0.06	(0.20)		0.18	(0.17)		0.42	(0.58)
NM	53	---			---			---
Prior therapy
Less	143	--			--			--			--		0.005
More	71	−2.9	(2.31)	NS	0.31	(0.14)	0.03	0.17	(0.12)	NS	−1.15	(0.41)
Gender
Female	96	--			--			--
Male	118	3.3	(1.28)	0.01	−0.23	(0.08)	0.005	−0.16	(0.06)	0.02	0.38	(0.23)	0.10
Scleroderma
No	205	--			--			--			--
Yes	9	7.6	(2.31)	0.02	−0.19	(0.20)	NS	−0.34	(0.17)	0.04	0.55	(0.59)	NS
Time post BMT
<18 years	129	--			--			--			--
>18 years	85	−0.5	(1.46)	NS	0.17	(0.09)	0.07	0.08	(0.07)	NS	−0.43	(0.26)	0.10

Abbreviations

CMS = composite mental score where higher values are better, depression where lower scores are better, anxiety where lower scores are better. Satis = satisfaction with life. Less prior therapy = first remission or no therapy and more therapy = second or subsequent remission therapy or relapse or cranial irradiation. Myeloid includes acute myelogenous leukemia, myelodysplastic syndrome, juvenile myelomonocytic leukemia. Lymphoid includes acute lymphoblastic leukemia, Hodgkin Disease, Non-Hodgkin lymphoma, CML = Chronic Mylogenous Leukemia, NM = non-malignant includes aplastic anemia, immune deficiency, red cell aplasia SEE = Standard Error of the Estimate

^*Numbers reflect mean differences relative to reference group.

---- = reference group