Table 2.
Summary of study population characteristics by biopsy category*
Biopsy category | |||||
---|---|---|---|---|---|
Characteristic | Benign, no atypia | Infiltrating cancer or DCIS | Premalignant | No biopsy (benign) | P |
Mean age at menarche, y† | 13 | 12 | 13 | 13 | .9997 |
Mean age at first pregnancy, y† | 25 | 22 | 24 | 24 | .8622 |
% Nulliparous | 79.1 | 100.0 | 66.7 | 75.8 | .9299 |
Mean age at diagnosis, y† | 36 | 38 | 38 | 35 | .0959 |
Menopausal status | .0307 | ||||
Premenopausal | 86 | 6 | 6 | 433 | |
Postmenopausal | 6 | 0 | 0 | 48 | |
Perimenopausal | 0 | 0 | 1 | 4 | |
Screening breast EIS result | <.001 | ||||
Negative | 87 | 4 | 4 | 473 | |
Positive | 5 | 2 | 3 | 13 | |
Clinical breast examination result | <.001 | ||||
No findings | 19 | 2 | 4 | 359 | |
Not suspicious | 55 | 1 | 2 | 124 | |
Suspicious | 18 | 3 | 1 | 3 | |
Hormone replacement therapy | .9460 | ||||
Current | 1 | 0 | 0 | 14 | |
Past | 1 | 0 | 0 | 3 | |
Never | 90 | 6 | 7 | 469 | |
Bra cup size | .0094 | ||||
A | 4 | 3 | 0 | 39 | |
B | 25 | 1 | 3 | 123 | |
C | 18 | 0 | 1 | 110 | |
D+ | 6 | 1 | 1 | 65 | |
Not recorded | 39 | 1 | 2 | 149 | |
Mammogram results | <.001 | ||||
BIRADS 0 | 3 | 0 | 3 | 8 | |
BIRADS I or II | 27 | 0 | 2 | 163 | |
BIRADS III | 6 | 0 | 0 | 30 | |
BIRADS IV | 26 | 3 | 2 | 4 | |
BIRADS V | 0 | 3 | 0 | 1 | |
No mammogram | 30 | 0 | 0 | 280 | |
Family history category | .1035 | ||||
One first degree | 7 | 1 | 0 | 51 | |
One second degree | 18 | 1 | 2 | 87 | |
One first degree and one or more second degree | 0 | 1 | 0 | 6 | |
Two or more first degree | 6 | 0 | 2 | 42 | |
Two or more second degree | 55 | 2 | 3 | 266 | |
No significant family history | 6 | 1 | 0 | 34 | |
Gail model 5-year risk category, % | <.001 | ||||
<1.66 | 86 | 2 | 5 | 441 | |
≥1.66 | 4 | 3 | 1 | 22 | |
Not recorded | 2 | 1 | 1 | 23 |
*BIRADS indicates Breast Imaging Reporting and Data System; EIS, electrical impedance scanning; and DCIS, ductal carcinoma in situ.
†P value of cancer and premalignant populations compared with benign population.