Table 4.
Association between Colorectal Cancer and Selected Reproductive Characteristics by Microsatellite Instability
|
MSI-H |
MSI-L/MSS |
||
---|---|---|---|---|
Gravidity/parity | Cases n (%) | OR (95% CI)a | Cases n (%) | OR (95% CI)a |
Nulligravid | 9 (6.6) | 1.36 (0.62–2.99) | 37 (8.4) | 1.19 (0.75–1.90) |
Nulliparous | 3 (1.8) | 1.32 (0.35–4.96) | 7 (1.6) | 0.81 (0.32–2.05) |
0 | 77 (58.3) | 1.00 (reference) | 239 (54.3) | 1.00 (reference) |
1 | 31 (20.4) | 0.85 (0.53–1.36) | 96 (22) | 0.80 (0.59–1.08) |
2+ | 18 (12.9) | 0.94 (0.53–1.68) | 61 (13.7) | 1.04 (0.72–1.49) |
ptrend | 0.3 | 0.2 |
Adjusted for age, family history of colorectal cancer, BMI, education, endoscopy screening, oral contraceptive use, hormone replacement therapy, smoking, and alcohol consumption.