Table 5.
The Genetic Subgroups Defined by the Step 2 PRIM Analysis in Women
| Genetic Subgroup | Overall | Subsample FS 1 | FS 2* | FS 3* |
|---|---|---|---|---|
| A560T832/T560T832 or A560T832/A560G832 | N=1503, I=77 | N=308, I=172 (134, 217) (FS 1–1) | N=348, I=98 | N=847, I=34 |
| A560T832/A560T832 or others† | N=2183, I=65 | N=456, I=116 (82, 143) (FS 1–2) | N=491, I=100 | N=1236, I=32 |
The subsample in italics indicates the significant genetic subgroup from subsample S 1. I indicates number of cases/1000 individuals at risk (CI).
A CI cannot be calculated because the PRIM did not define this contrast in these subsamples. (See Dyson et al19 for more details.)
“Others” is the group of 5′ genotypes that does not include A560T832/T560T832, A560T832/A560G832, or A560T832/A560T832.