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. Author manuscript; available in PMC: 2010 Apr 8.
Published in final edited form as: Dev Biol. 2009 Jan 20;328(1):13–23. doi: 10.1016/j.ydbio.2008.12.041

Fig. 6. Expression of proximal markers in wild type and fused mutant BA1.

Fig. 6

(A,B) Lateral and frontal views of wild type Fgf8 expression in the oral epithelium of the proximal region of BA1 at E9.5. (C,D) The expression of Fgf8 is preserved in the proximal region of mutant embryos of class B and extends across the fused BA1 tissue, reflecting a shift of expression domain. (E,F) The expression of Fgf8 is significantly reduced in the proximal region of mutant embryos of class C, but present in the distal region. (G,H) Lateral and frontal views of wild type Barx1 expression in the mesenchyme of the proximal region of BA1 at E9.5. (I,J) Expression domain of Barx1 is extended across the midline in Twsg1 mutants. (K,L) Lateral and frontal views of wild type Nog expression in the oral epithelium of BA1 at E10.5. (I,J) Expression of Nog is extended across the fused BA1 in Twsg1−/− embryos. Scale bar: 200 μm in A-J and 100 μm in K-N.