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. Author manuscript; available in PMC: 2010 Apr 8.

Published in final edited form as: Chem Biol. 2008 May;15(5):493–500. doi: 10.1016/j.chembiol.2008.04.005

Table 2.

70S assay kinetic data (pH 8.5, 37 °C)

		60% DMSO		No DMSO

	pK_a	k_pep (s⁻¹)	K_M (mM)	k_pep (s⁻¹)	K_M (mM)

Pmn(β,β-F-Phe)	<5.0	22.4	12.5	36.9	1.3
Pmn(β-F-Phe)	5.6	-	-	37.5	2.9
Pmn(3,4-Cl-Phe)	6.5	20.4	12.7	-	-
Pmn(3,4-F-Phe)	6.6	21.1	12.1	-	-
Pmn	6.9	13.2	6.1	12.0	2.5
Pmn(Phe)	7.0	14.7	8.3	12.3	3
Pmn(4-CH₃-Phe)	7.1	21.5	17.9	-	-