Figure 4. Effects of Age and Caloric Restriction on Rates of Mitochondrial Oxygen Consumption, Mitochondrial Superoxide Anion and Hydrogen Peroxide Production, and Concentrations of Protein Carbonyls in the Brain in Mice.

Data are for male C57BL/6NNia mice either fed ad libitum or subjected to a 40 percent reduction in caloric intake from four months of age. $·{\text{O}}_2^{-}$ denotes superoxide anion, O₂ oxygen, and H₂O₂ hydrogen peroxide. The bars represent standard errors. Data were adapted from Sohal et al.⁴⁷