Table 1.
Statistical association of clinical factors and HPV status
| Category | Variable | Patients (#) | HPV + (%) | p-value |
|---|---|---|---|---|
| Age | < = 40 | 22 | 1 (4.5) | 0.02 |
| >40 and <60 | 28 | 10 (35.7) | ||
| > = 60 | 42 | 8 (19) | ||
| Sex | F | 28 | 4 (14.3) | 0.32 |
| M | 64 | 15 (23.4) | ||
| Smoking | Y | 53 | 11 (20.8) | 0.59 |
| N | 32 | 6 (18.8) | ||
| Former | 5 | 0 (0) | ||
| Alcohol | Y | 46 | 9 (19.6) | 0.47 |
| N | 19 | 2 (10.5) | ||
| Former | 6 | 0 (0) | ||
| Other | 18 | 5 (27.8) | ||
| Stage | I | 6 | 0 (0) | 0.12 |
| II | 22 | 1 (4.5) | ||
| III | 21 | 5 (23.8) | ||
| IV | 40 | 10 (25) | ||
| Tumor Differentiation | Well | 1 | 0 (0) | 0.51 |
| Moderately | 68 | 12 (17.6) | ||
| Poorly | 18 | 5 (27.8) | ||
| Other | 5 | 2 (40) | ||
| Site | Tongue | 29 | 1 (3.4) | < 0.0001 |
| FOM | 8 | 1 (12.5) | ||
| FOM+Tongue | 6 | 0 (0) | ||
| Oropharynx (Base of Tongue) | 22 | 16 (72.7) | ||
| Larynx/Pharynx/Nasopharynx | 17 | 1 (5.9) | ||
| Other | 10 | 0 (0) | ||
| Node | + | 43 | 15 (34.9) | < 0.0001 |
| - | 46 | 1 (2.2) | ||
| Outcome | Alive | 83 | 17 (20.5) | 0.24 |
| Dead | 7 | 0 (0) | ||
| HPV | + | 19 | ||
| - | 73 |
Clinical categories and the variables were examined for significant associations with HPV status. Statistical significance was assessed by Fisher's exact and Pearson's chi-square tests (p ≤ 0.05). M - Male; F -- Female; Y -- Yes; N -- No; FOM -- Floor of Mouth. Unknown values were not included in analysis.