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. 2010 Mar 18;10:30. doi: 10.1186/1471-213X-10-30

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Copyright ©2010 Scholz et al; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Virtual importance in the projection plot (VIP). The VIP shows the role of identified peptides in the separation of the four age and EE₂exposure PLS/DA classes (ed12C, ed12E, ed17C, ed17E). The preprotachykinin-1 neuropeptide K (NPK) is the top candidate among identified peptides for being affected by both age and EE₂exposure. Values above one are the most relevant for the separation of all classes. Unidentified peptides are not shown. Error bars designate confidence intervals derived by jack knifing.