Figure 5.

Embryonic phenotype of double mutants. (A-D) Abdominal segments from late stage embryos stained with 22C10 (green) and anti-Cpo (magenta in B', C', D). (A) OregonR (wild type) embryo with lateral Ch and ES neurons indicated. (B, B') Homozygous ato¹ mutant embryo, with neuron (B, B'), scolopale and cap cells (B, B') of lch5a indicated, as well as adjacent ES neurons. (C.C') Double homozygous cato⁵³⁶; ato¹ mutant embryo, with ES neurons visible but no lch5a organ. (D) Embryo homozygous for ase¹ and heterozygous for cato⁵³⁶, with lch5 Ch clusters reduced from five to four Ch organs. (E) Model for the dependence of C1 cell development on cato, ato and sc. See text for details.