Table 3.
Overlapping gene pairs on opposing strands
Group | N | Co-expressiona | mRNA abundanceb | P (compared to random pairs)c | |
---|---|---|---|---|---|
1 | 3' overlap | 948 | -0.019 | 8.39 | 0.0020 |
2 | 5' overlap | 23 | 0.140 | 7.99 | 0.142 |
3 | fully containedd | 17 | -0.084 | 7.30 | 0.103 |
aAverage Pearson correlation coefficient
b average mRNA abundance for all genes is 7.73 (log2 signal intensity).
c To derive a Null expectation, we analyzed 100,000 pairs of randomly chosen genes; mean Pearson correlation of this random dataset is 0.014. P-values from Wilcoxon rank sum tests.
d the shorter gene is fully contained in the longer gene (but transcribed from the opposite DNA strand)