Table.

Hazard ratios (95% confidence intervals) in Paris prospective study cohort (864 men, 48-52 years, 18 year follow up) of factors predictive of death from all causes, from cardiovascular disorders and from malignant disorders from a multivariate Cox model analysis. Variables are presented in order of entry into model using a forward method after adjustment for age

Factors in order of entry into model	Hazard ratios	P value
All causes
Systolic blood pressure (mm Hg)	1.02 (1.01 to 1.02)	<0.0001
Smoking (cigarettes/day)	1.04 (1.03 to 1.06)	<0.0001
Fasting fatty acids (mg/l)*	2.45 (1.61 to 3.72)	<0.0001
2 hour growth hormone (μg/l)‡	2.54 (1.51 to 4.27)	0.002
Mean corpuscular volume (fl)†:
Mean v mean+SD	1.21 (0.97 to 1.51)	0.07
Mean v mean−SD	0.95 (0.76 to 1.18)
Fasting growth hormone (μg/l)‡	1.50 (1.12 to 2.02)	0.009
Cardiovascular disorders
Diastolic blood pressure (mm Hg)	1.04 (1.02 to 1.05)	<0.0001
Mean corpuscular volume (fl)	1.06 (1.01 to 1.12)	0.02
Fasting growth hormone (μg/l)‡	1.79 (1.00 to 3.18)	0.05
Smoking (cigarettes/day)	1.03 (1.00 to 1.06)	0.06
Malignant disorders
Smoking (cigarettes/day)	1.06 (1.04 to 1.08)	<0.0001
Fasting fatty acids (mg/l)*	2.88 (1.49 to 5.57)	0.002
Mean corpuscular volume (fl)	1.06 (1.01 to 1.10)	0.01
2 hour growth hormone (μg/l)‡	2.59 (1.17 to 5.73)	0.04

P values and hazard ratios are adjusted for variables already in the model.  

^*Log₁₀ transformed.  

^†Non-linear relation (quadratic), hazard ratio, and P value were calculated for mean (98.7 fl) v mean+SD (98.7+5.7=104.4 fl) and for mean v mean−SD (93.0 fl).  

^‡Above v below the median at 0 hour (0.5 μg/l) and the 95th centile at 2 hours (1.1 μg/l).