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. 2010 Mar 17;11:137. doi: 10.1186/1471-2105-11-137

Table 5.

Statistical Analysis of the Improvement in Rank

Therapeutic Use N Mean Improvement StdDev tValue P
analgesic 29 90.43 117.55 4.14 0.0003
anti-inflammatory 160 30.12 115.04 3.31 0.0011
anti-psychotic (neurole) 69 25.57 73.36 2.90 0.0051
immunosuppressive agent 67 7.96 40.42 1.61 0.1120
tranquilizer 68 14.43 73.95 1.61 0.1124
cardiovascular agent 22 10.82 69.37 0.73 0.4726
anti-neoplastic 54 10.33 114.65 0.66 0.5106
anti-convulsant 144 -4.50 92.09 -0.59 0.5585
anti-proliferative 86 -1.86 77.86 -0.22 0.8252

A paired t-test was performed to analyze the difference in the rank of true positives returned by the direct and indirect method. N is the number of true positives found within the top 100 results across the whole therapeutic group. Improvement is the average improvement (rank direct - rank indirect).