Appendix Table A1.
Baseline Characteristics of Overall HAT Patient Population versus Quality of Life Subset
| Overall HAT (n=7001) | HAT QOL Substudy* (n=948) | |
|---|---|---|
| Patients | ||
| Age, years median (interquartile range) | 62 (54, 70) | 62 (54, 70) |
| Female | 17% (1220) | 17% (162) |
| Racial or ethnic minority | 13% (906) | 12% (114) |
| Time since most recent anterior MI | ||
| ≤1 Month | 10% (566) | 11% (87) |
| >1 Month to 3 months | 10% (590) | 9% (72) |
| >3 Months to 6 months | 9% (554) | 9% (78) |
| >6 Months to 1 year | 11% (670) | 10% (80) |
| >1 Year | 60% (3578) | 62% (509) |
| Employment Status | ||
| Full time | 33% (2284) | 32% (302) |
| Part time | 10% (697) | 11% (104) |
| Not employed | 57% (4020) | 57% (542) |
| Estimated daily time alone at home – hr median (interquartile range) | 1.5 (0.5, 4.0) | 1.5 (0.5, 4.0) |
| Estimated daily time away from home – hr median (interquartile range) | 4.0 (2.0, 8.0) | 3.5 (2.0, 7.5) |
| Previous procedures - no. (%) | ||
| Percutaneous coronary revascularization | 53% (3742) | 55% (526) |
| Coronary artery bypass grafting | 27% (1867) | 27% (257) |
| Coexisting conditions - no. (%) | ||
| Hypertension | 54% (3769) | 52% (496) |
| Diabetes | 21% (1504) | 22% (206) |
| Hypercholesterolemia | 79% (5557) | 80% (762) |
| Stroke | 6% (437) | 7% (66) |
| Ejection fraction measured –% (no.) | 80% (5624) | 80% (763) |
| Left ventricular ejection fraction - % median (interquartile range) | 45 (35, 55) | 45 (37, 55) |
| Body mass index – kg.m−2 median (interquartile range) | 27.7 (25.0, 30.9) | 27.7 (25.3, 30.7) |
| NYHA Class – no. (%) | ||
| I | 65% (4570) | 65% (614) |
| II | 29% (2053) | 30% (282) |
| III | 5% (367) | 5% (52) |
| IV | <1% (11) | 0% (0) |
| Type of myocardial infarction – no (%) | ||
| Anterior Q-wave | 64% (4509) | 66% (625) |
| Anterior non-Q-wave | 36% (2491) | 34% (323) |
| Use of medication – no. (%) | ||
| Beta-blocker (other than sotalol or amiodarone) | 79% (5531) | 80% (759) |
| ACE inhibitor or angiotensin-receptor blocker | 82% (5719) | 81% (765) |
| Statin | 89% (6241) | 89% (844) |
| Daily use of aspirin | 87% (6063) | 87% (823) |
| Digoxin | 7% (489) | 6% (60) |
| Warfarin | 18% (1249) | 18% (169) |
| Any antiarrhythmic drug | 4% (298) | 5% (47) |
| Spouse or companion | ||
| Relationship to patient – no. (%) | ||
| Spouse | 88% (6150) | 89% (844) |
| Companion | 4% (303) | 4% (40) |
| Other | 8% (548) | 7% (64) |
| Age – yr median (interquartile range) | 58 (50, 66) | 58 (50, 66) |
| Employment Status – no. (%) | ||
| Full time | 32% (2223) | 31% (295) |
| Part time | 17% (1196) | 16% (149) |
| Not employed | 51% (3582) | 53% (504) |
| Estimated daily time away from home – hr median (interquartile range) | 4.0 (2.0, 7.5) | 3.0 (2.0, 7.0) |
| Completed secondary school – no. (%) | 81% (5682) | 82% (779) |
*
Defined as any QOL substudy-randomized patient that did not refuse to complete at least one of the two patient-oriented questionnaires at baseline