Appendix Table A5.

EuroQoL Scores of Overall HAT Patient Population versus Quality of Life Subset

	Overall HAT	Non-QoL HAT	QoL HAT	P-value comparing Non-QOL to QOL groups
EuroQoL Visual Analog Scale
0–100 scale; 0=worst imaginable health, 100=perfect health
Baseline
No. of patients	6981	5978	1003	0.61
Median (interquartile range)	80.0 (70.0, 90.0)	80.0 (70.0, 90.0)	80.0 (70.0, 90.0)
Mean ± standard deviation	75.9 ± 16.2	76.0 ± 16.2	75.5 ± 16.3
Year 1
No. of patients	6319	5405	914	0.79
Median (interquartile range)	80.0 (70.0, 90.0)	80.0 (70.0, 90.0)	80.0 (70.0, 90.0)
Mean ± standard deviation	78.3 ± 15.9	78.4 ± 15.8	77.8 ± 16.6
Year 2
No. of patients	5851	5010	841	0.27
Median (interquartile range)	80.0 (70.0, 90.0)	80.0 (70.0, 90.0)	80.0 (70.0, 90.0)
Mean ± standard deviation	78.0 ± 16.2	78.1 ± 16.3	77.5 ± 16.1
EuroQoL Single Summary Index (Health State)
Baseline
No. of patients	6969	5966	1003	0.65
Median (interquartile range)	0.88 (0.74, 1.00)	0.88 (0.75, 1.00)	0.88 (0.73, 1.00)
Mean ± standard deviation	0.85 ± 0.20	0.85 ± 0.20	0.85 ± 0.21
Year 1
No. of patients	6338	5422	916	0.42
Median (interquartile range)	0.88 (0.74, 1.00)	0.88 (0.74, 1.00)	0.88 (0.73, 1.00)
Mean ± standard deviation	0.85 ± 0.21	0.85 ± 0.21	0.84 ± 0.22
Year 2
No. of patients	5916	5060	856	0.23
Median (interquartile range)	1.00 (0.74, 1.00)	1.00 (0.74, 1.00)	0.88 (0.73, 1.00)
Mean ± standard deviation	0.85 ± 0.21	0.85 ± 0.21	0.84 ± 0.23