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Expression of HIF-1α, CD68, and CD31 in RA synovial tissue. Representative pictures of immunohistochemical staining of RA synovial tissue obtained after total joint replacement. Consecutive (A, B, C) sections were treated according to standard procedures for immuno-histochemistry, and stained for HIF-1α (A, D), macrophage marker CD68 (B), and endothelial cell marker CD31 (C). Magnification A-C 200×, D 400×.
