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Telomere length regulation. (A) Type C (capped). A telomere in a t loop is not a substrate for telomerase. The longer the telomere, the higher the chance that it is in this state. (B) Type U (uncapped). An open telomere is a substrate for telomerase. The shorter the telomere, the higher the chance that it is in this state. (C) Type UT (telomere–telomerase complex). A telomerase-bound telomere is elongated by telomerase.
