Table 2.
Dietary glycemic index, dietary glycemic load and incidence of myocardial infarction
Median | Cases | Person-years | Age-adjusted incidence rate ratio (95% CI)* | Multivariable-adjusted incidence rate ratio (95% CI)† | |
---|---|---|---|---|---|
Dietary glycemic index | |||||
Quartile 1 | 69.5 | 229 | 78,498 | 1 (reference) | 1 (reference) |
Quartile 2 | 73.3 | 246 | 78,575 | 1.04 (0.87–1.25) | 1.06 (0.88–1.27) |
Quartile 3 | 76.1 | 295 | 77,914 | 1.10 (0.93–1.31) | 1.11 (0.92–1.33) |
Quartile 4 | 79.9 | 368 | 76,515 | 1.16 (0.98–1.37) | 1.12 (0.92–1.35) |
P-trend | 0.06 | 0.24 | |||
Dietary glycemic load | |||||
Quartile 1 | 131 | 229 | 78,423 | 1 (reference) | 1 (reference) |
Quartile 2 | 150 | 264 | 78,187 | 1.06 (0.89–1.27) | 1.14 (0.93–1.39) |
Quartile 3 | 164 | 296 | 77,858 | 1.07 (0.90–1.27) | 1.18 (0.94–1.50) |
Quartile 4 | 184 | 349 | 77,035 | 1.09 (0.92–1.29) | 1.22 (0.90–1.65) |
P-trend | 0.34 | 0.23 |
Cox proportional hazards model accounting for age.
Additionally adjusted for education (less than high school, high school, university), BMI (linear term), physical activity (linear term), cigarette smoking (current, past, never), living alone (yes, no), postmenopausal hormone use (yes, no), aspirin use (yes, no), total energy intake (linear term), alcohol intake (linear term), fiber intake (linear term), saturated fat (linear term), polyunsaturated fat (linear term), protein (linear term), carbohydrate (linear term, dietary glycemic index only), family history of myocardial infarction before 60 years (yes, no), self-reported history of hypertension (yes, no), and self-reported history of high cholesterol (yes, no)