Table 3.

Apical Cl⁻ channels in principal cells from wild-type and transgenic mice

Parameter	Wild-type	ΔF508-CFTR	ROMK−/−
No. of patches*	37	13	19
No. of patches with Cl− channels (%)	15 (40.5)	0	9 (47.4)
Cl− channel NPo, mean ± SEM	0.24 ± 0.02	0	0.27 ± 0.03

*Inside-out patches using symmetrical bath and pipette solutions containing 145 mM NMDG-Cl and held at -Vp = 60 mV.