Table 1.
Treatment | Incidence | Day of onset | Peak severity | CDI |
Control | 100% (7/7) | 11 ± 1 | 3.3 ± 0.4 | 43 ± 7 |
2.5 kJ/m2 | 100% (11/11) | 12 ± 3 | 3.3 ± 0.5 | 42 ± 9 |
5.0 kJ/m2 | 92% (11/12) | 14 ± 3 | 3.4 ± 0.6 | 36 ± 15 |
Female C57BL/6 mice on a regular chow diet were treated once daily for 7 days with either 2.5 or 5.0 kJ/m2 UVB before immunization with MOG35–55. The cumulative disease score (CDI) was calculated by summing all of the clinical scores for the entire experiment and dividing by the number of mice for each group. The clinical data demonstrate the mean ± SD from one representative of three individual experiments.