Table 2.

Quantitative microPET and ground tissue metabolite data.

RATS (n = 3)			MICE (n = 7)
Brain region	SUVR*	11C-(2b)-6-O-sulfate (% of total activity)	Organ	SUVR†	11C-(2b)-6-O-sulfate (% of total activity)
Cortex1‡	1.77 ± 0.35	57.4 ± 4.4	Brain	0.17 ± 0.05	3.1 ± 8.2
Cortex2§	1.72 ± 0.28	65.6 ± 7.7	Lungs	0.37 ± 0.13	72.9 ± 18.9
Subcortical	2.39 ± 0.45	64.8 ± 1.8	Liver	2.2 ± 0.6	82.7 ± 5.1
Cerebellum	1	34.7 ± 4.3	Kidney	1.8 ± 0.4	82.2 ± 11.5
Brainstem	1.58 ± 0.18	35.5 ± 4.7	Testis	¶	58.9 ± 25.3
Plasma	—	66.3 ± 6.2∥	Plasma	—	78.5 ± 6.8

^*Normalized to cerebellum.

^†Normalized to whole body.

^‡Frontal cortex.

^§Superior cortical regions.

^¶Testis could not be measured within the field of view.

^∥A minor, more polar component (7 ± 10%) consistent with ¹¹C-(2b)-6-O-glucuronidate was occasionally found only in rat plasma.