Table 4.
Overtransmitted haplotypes by ethnicity
| Gene | SNP1 | SNP ordera | SNP2 | SNP order | Overtransmitted haplotype | P-valueb |
|---|---|---|---|---|---|---|
| European Americans | ||||||
| Wnt3 | rs142167 | 1 | rs199525 | 3 | 2.1 | 0.049 |
| Wnt3 | rs7216231 | 2 | rs199525 | 3 | 2.1 | 0.033 |
| Wnt3 | rs199525 | 3 | rs70602 | 4 | 1.2 | 0.05 |
| Wnt3A | rs708111 | 1 | rs752107 | 5 | 2.1 | 0.010 |
| Wnt3A | rs708114 | 2 | rs752107 | 5 | 1.1 | 0.014 |
| Wnt3A | rs3094912 | 3 | rs752107 | 5 | 1.1 | 0.037 |
| Wnt3A | rs3121310 | 4 | rs752107 | 5 | 2.1 | 0.017 |
| Wnt3A | rs752107 | 5 | rs1745420 | 6 | 1.2 | 0.001 |
| Wnt8A | rs4835761 | 1 | rs2306110 | 3 | 1.1 | 0.05 |
| Wnt11 | rs663746 | 1 | rs1533767 | 3 | 2.2 | 0.047 |
| Wnt11 | rs1533763 | 2 | rs596339 | 5 | 2.2 | 0.012 |
| Wnt11 | rs1533767 | 3 | rs1568507 | 6 | 2.2 | 0.013 |
| Hispanics | ||||||
| Wnt3 | rs199498 | 6 | rs9890413 | 10 | 2.2 | 0.047 |
| Wnt3A | rs708111 | 1 | rs3121310 | 4 | 1.1 | 0.022 |
| Wnt3A | rs708111 | 1 | rs752107 | 5 | 1.1 | 0.008 |
| Wnt3A | rs708111 | 1 | rs1745420 | 6 | 1.2 | 0.007 |
| Wnt3A | rs708114 | 2 | rs3094912 | 3 | 2.1 | 0.004 |
| Wnt3A | rs708114 | 2 | rs1745420 | 6 | 2.2 | <0.001 |
| Wnt3A | rs3094912 | 3 | rs3121310 | 4 | 1.1 | <0.001 |
| Wnt3A | rs3094912 | 3 | rs752107 | 5 | 1.1 | <0.001 |
| Wnt3A | rs3094912 | 3 | rs1745420 | 6 | 1.2 | 0.003 |
| Wnt3A | rs3121310 | 4 | rs752107 | 5 | 1.1 | 0.027 |
| Wnt3A | rs3121310 | 4 | rs1745420 | 6 | 1.2 | <0.001 |
| Wnt3A | rs752107 | 5 | rs1745420 | 6 | 1.2 | <0.001 |
| Wnt8A | rs4835761 | 1 | rs2306110 | 3 | 2.2 | 0.049 |
aSNP order: order of SNP within the gene.
bAll SNPs with P < 0.05 are shown and P ≤ 0.007 are bolded.