TABLE 2.

EFFECT OF PROTEOLYTIC ENZYMES AND STANDARD DRUG ON COTTON PELLET INDUCED GRANULOMA FORMATION

Treatment	Dose (mg/kg)	Mean granuloma wt (mg/100 g)	% Inhibition
Control	Normal Saline	45.54 ± 1.19
Aspirin	200.00	27.66 ± 2.60	39.24*
Chymotrypsin	18.00	26.46 ± 2.88	41.88*
Trypsin	2.88	29.22 ± 2.43	35.85*
Serratiopeptidase	0.90	25.15 ± 1.13	44.77*
Chymotrypsin + Aspirin	9.00 + 54.00	28.88 ± 1.82	36.58*
Trypsin + Aspirin	1.44 + 54.00	30.14 ± 0.58	33.00*
Serratiopeptidase + Aspirin	0.45 + 54.00	28.10 ± 4.23	38.28*

Values are mean ± SEM; n = 6 animals in each group;

^*p < 0.05 when compared to control