TABLE 3.

EFFECT OF PROTEOLYTIC ENZYMES AND STANDARD DRUG ON GASTRIC MUCOSA (ULCER INDEX)

Treatment	Dose (mg/kg)	Mean ulcer index ± SEM	% Inhibition
Control	Normal Saline	10.00 ± 6.32
Aspirin	200.00	40.00 ± 0.00
Chymotrypsin	18.00	5.00 ± 0.60	50.00*
Trypsin	2.88	5.60 ± 0.66	44.00*
Serratiopeptidase	0.90	4.21 ± 0.26	57.90*
Chymotrypsin + Aspirin	9.00 + 54.00	26.42 ± 5.83	33.95#
Trypsin + Aspirin	1.44 + 54.00	30.00 ± 4.21	25.00#
Serratiopeptidase + Aspirin	0.45 + 54.00	23.33 ± 7.602	41.67#

Values are mean ± SEM; n = 6 animals in each group;

^*p < 0.05 when compared to control and

^#p < 0.05 when compared to aspirin